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H Ralph Schumacher Selected Research

rilonacept

8/2014Rilonacept for gout flare prevention in patients receiving uric acid-lowering therapy: results of RESURGE, a phase III, international safety study.
7/2013Rilonacept for gout flare prevention during initiation of uric acid-lowering therapy: results from the PRESURGE-2 international, phase 3, randomized, placebo-controlled trial.
2/2013Rilonacept in the treatment of acute gouty arthritis: a randomized, controlled clinical trial using indomethacin as the active comparator.
10/2012Rilonacept (interleukin-1 trap) for prevention of gout flares during initiation of uric acid-lowering therapy: results from a phase III randomized, double-blind, placebo-controlled, confirmatory efficacy study.
3/2012Rilonacept (interleukin-1 trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: results of a phase II randomized, double-blind, placebo-controlled trial.

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H Ralph Schumacher Research Topics

Disease

47Gout
01/2017 - 06/2004
14Pain (Aches)
09/2015 - 02/2002
13Hyperuricemia
12/2016 - 03/2005
13Inflammation (Inflammations)
11/2012 - 06/2002
10Arthritis (Polyarthritis)
03/2014 - 09/2002
9Osteoarthritis
09/2013 - 01/2004
8Infections
12/2014 - 01/2002
7Gouty Arthritis
02/2013 - 02/2002
6Knee Osteoarthritis
09/2013 - 12/2002
5Rheumatoid Arthritis
12/2014 - 01/2005
5Joint Diseases (Joint Disease)
03/2014 - 09/2002
4Rheumatic Diseases (Rheumatism)
12/2016 - 08/2014
3Injection Site Reaction
08/2014 - 10/2012
3Synovitis
03/2014 - 07/2004
2Multiple Myeloma
03/2014 - 12/2013
2Reactive Arthritis (Reiter Disease)
12/2010 - 08/2005
2Disease Progression
07/2008 - 06/2003
2Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2007 - 08/2006
2Hypertension (High Blood Pressure)
02/2007 - 09/2006
1Cysts
09/2015
1Mobility Limitation (Difficulty Walking)
09/2015
1Erythema
09/2015
1Hepatitis
12/2014
1Tuberculosis (Tuberculoses)
08/2014
1Hypersensitivity (Allergy)
08/2014
1Opportunistic Infections (Opportunistic Infection)
08/2014
1Hypoxia (Hypoxemia)
10/2011
1Hypoparathyroidism
11/2010
1Dizziness (Lightheadedness)
11/2008
1Diarrhea
11/2008
1Necrosis
01/2008
1Peripheral Arterial Disease
08/2007
1Glucose Intolerance
02/2007
1Proteinuria
02/2007
1Body Weight (Weight, Body)
09/2006
1Hypertriglyceridemia
09/2006
1Hypercholesterolemia
09/2006
1Diabetes Mellitus
08/2006
1Obesity
08/2006

Drug/Important Bio-Agent (IBA)

40Uric Acid (Urate)IBA
01/2017 - 03/2005
11Allopurinol (Remid)FDA LinkGeneric
08/2014 - 12/2005
10ColchicineFDA LinkGeneric
12/2016 - 03/2005
8FebuxostatFDA Link
02/2010 - 03/2005
6Adrenal Cortex Hormones (Corticosteroids)IBA
10/2006 - 07/2004
5rilonaceptFDA Link
08/2014 - 03/2012
5Messenger RNA (mRNA)IBA
10/2011 - 01/2002
5Xanthine OxidaseIBA
02/2010 - 03/2005
5Pharmaceutical PreparationsIBA
09/2006 - 08/2004
4Interleukin-1 (Interleukin 1)IBA
07/2013 - 01/2005
4Indomethacin (Indometacin)FDA LinkGeneric
02/2013 - 06/2002
3Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
01/2015 - 06/2004
3Antirheumatic Agents (DMARD)IBA
12/2014 - 07/2004
3purineIBA
04/2009 - 07/2005
3CreatinineIBA
11/2008 - 09/2006
3Anti-Inflammatory Agents (Anti-Inflammatories)IBA
07/2008 - 10/2006
3CytokinesIBA
01/2008 - 09/2002
3DiureticsIBA
02/2007 - 08/2006
3Adrenocorticotropic Hormone (ACTH)FDA Link
10/2006 - 04/2006
3Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
09/2005 - 06/2004
2SugarsIBA
01/2017 - 12/2016
2Amyloid (Amyloid Fibrils)IBA
03/2014 - 12/2013
2InterleukinsIBA
02/2013 - 10/2011
2Celecoxib (Celebrex)FDA Link
09/2012 - 02/2006
2Triglycerides (Triacylglycerol)IBA
11/2007 - 02/2007
2Proteoglycans (Proteoglycan)IBA
09/2004 - 01/2004
2EtoricoxibIBA
06/2004 - 06/2002
2Complementary DNA (cDNA)IBA
01/2004 - 09/2002
2RNA (Ribonucleic Acid)IBA
01/2004 - 09/2002
1SteroidsIBA
01/2015
1Antiviral Agents (Antivirals)IBA
12/2014
1Leflunomide (Arava)FDA LinkGeneric
12/2014
1canakinumabFDA Link
11/2012
1ORALIT (ORS)IBA
11/2012
1Analgesics (Analgesic Drugs)IBA
09/2012
1AutoantibodiesIBA
08/2012
1FibrinIBA
08/2012
1IsomerasesIBA
10/2011
1Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA
10/2011
1ametantrone (HAQ)IBA
07/2011
1Biomarkers (Surrogate Marker)IBA
07/2011
1Indicators and Reagents (Reagents)IBA
07/2011
1CCR5 Receptors (CCR5 Receptor)IBA
12/2010
1DNA (Deoxyribonucleic Acid)IBA
12/2010
1AntibodiesIBA
11/2010
1Uricosuric AgentsIBA
02/2010
1Adenine phosphoribosyltransferase deficiencyIBA
05/2009
1Transcription Factors (Transcription Factor)IBA
01/2008
1Interleukin-6 (Interleukin 6)IBA
01/2008
1LipidsIBA
11/2007
1Acute-Phase Proteins (Acute-Phase Protein)IBA
03/2007
1CholesterolIBA
02/2007
1Prostaglandin D2IBA
01/2007
1Urea (Carbamide)FDA LinkGeneric
09/2006
1Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
08/2006

Therapy/Procedure

25Therapeutics
12/2016 - 02/2002
4Injections
11/2005 - 12/2002
2Subcutaneous Injections
08/2014 - 10/2012
1Duration of Therapy
11/2013
1Physical Therapy Modalities (Physical Therapy Technique)
09/2013
1Tai Ji (Tai Chi Chuan)
10/2010